The first of six inbound transfers to Georgetown following the 2021-22 season, Brandon Murray played at Baltimore Polytechnic Institute before a prep year at IMG Academy. He spent his freshman season at LSU, averaging 10.0 points per game on 42 percent shooting from the field and 33 percent from three point range.

An all-SEC freshman team selection, Murray was one of 11 LSU players who announced transfers following Will Wade's dismissal on NCAA recruiting violations. Murray was recruited by new Georgetown assistant Kevin Nickelberry, an assistant under Wade last season, and as seen as a immediate replacement for Aminu Mohammed, who left Georgetown in an unsuccessful effort to be selected in the NBA Draft.

Widely expected to be the team's lead scoring option to rebuild from a 6-25 season in 2021-22, Murray finished second in scoring behind Primo Spears last season, struggling from the field (37 percent in Big East play, 39 percent overall) and the foul line (64 percent) en route to per game averages of 13.7 points, 3.9 rebounds, and 3.2 assists. Murray led the Hoyas in scoring in seven games this season but was visibly lacking in games down the stretch, shooting 6 for 25 in the final three games of the season.

Murray announced he would enter the transfer portal in March 2023, signing with Ole Miss the following month.