The following are the 60 largest upsets as defined by Associated Press rankings between the schools. In the first table, these are 30 Georgetown wins as an unranked opponent over a ranked opponent. In the second table, these were 30 Georgetown losses when facing an unranked opponent. Games shaded in blue were in NCAA post-season play.

Georgetown Upsets Over Ranked Opponents

Date   Score       Opponent Rank Location Arena Attendance
12/27/1963 W 69 58 vs Loyola (IL) 1 Philadelphia, PA Palestra
1/21/2006 W 87 84 Duke 1 Washington, DC MCI Center 20,035
2/13/1980 W 52 50 at Syracuse 2 Syracuse, NY Manley Field House 9,521
1/19/2015 W 78 58 Villanova 4 Washington, DC Verizon Center 13,872
1/26/2013 W 53 51 Louisville 5 Washington, DC Verizon Center 17,474
1/19/2016 W 81 72 at Xavier 5 Cincinnati, OH Cintas Center 9,906
2/1/2014 W 64 60 vs Michigan St. 7 New York, NY Madison Sq. Garden 12,561
11/23/2011 W 91 88 OT vs Memphis 8 Lahaina, HI Civic Center 2,400
2/28/2009 W 56 54 at Villanova 10 Philadelphia, PA Wachovia Center 20,378
11/24/2013 W 84 80 vs VCU 10 San Juan, PR Clemente Coliseum 7,642
2/13/1988 W 71 69 Syracuse 11 Landover, MD Capital Centre 19,025
2/26/1995 W 81 78 at Syracuse 11 Syracuse, NY Carrier Dome 31,143
11/19/2012 W 78 70 vs UCLA 11 Brooklyn, NY Barclays Center 10,071
2/4/1976 W 74 73 OT St. John's 12 Washington, DC McDonough Gym
12/27/1977 W 79 65 vs Holy Cross 12 New York, NY Madison Sq. Garden
3/9/2000 W 76 72 vs Syracuse 12 New York, NY Madison Sq. Garden 18,406
12/1/2011 W 57 55 at Alabama 12 Tuscaloosa, AL Coleman Coliseum 15,853
1/17/1970 W 72 68 Columbia 13 Washington, DC McDonough Gym
3/4/2014 W 75 63 Creighton 13 Washington, DC Verizon Center 12,105
11/21/2016 W 65 61 vs Oregon 13 Lahaina, HI Lahaina Civic Ctr. 2,400
2/7/1994 W 60 56 Syracuse 14 Landover, MD US Air Arena 11,629
1/27/1997 W 78 67 Villanova 14 Landover, MD US Air Arena 11,891
1/28/2002 W 75 60 Syracuse 14 Washington, DC MCI Center 14,889
12/5/2015 W 79 72 Syracuse 14 Washington, DC Verizon Center 18,231
11/26/2014 W 66 65 OT vs Florida 15 Nassau, Bahamas Imperial Arena 3,240
1/12/2002 W 70 43 at Boston College 16 Chestnut Hill, MA Conte Forum 8,606
1/5/2005 W 67 64 at Pittsburgh 16 Pittsburgh, PA Petersen Center 11,425
1/25/2017 W 71 51 Creighton 16 Washington, DC Verizon Center 8,185
2/11/1978 W 83 82 Detroit 17 Washington, DC McDonough Gym
1/6/2007 W 66 48 Notre Dame 17 Washington, DC Verizon Center 15,506

Georgetown Upset By Unranked Opponents

Date   Score       Opponent GU Rank Location Arena Attendance
4/1/1985 L 64 66 vs Villanova 1 Lexington, KY Rupp Arena 23,124
2/21/1984 L 71 75 St. John's 2 Landover, MD Capital Centre 11,136
1/28/1989 L 80 82 at Louisiana St. 2 New Orleans, LA Superdome 66,144
2/11/1989 L 74 79 at Pittsburgh 2 Pittsburgh, PA Civic Arena 16,669
1/20/1990 L 65 70 at Connecticut 2 Hartford, CT Hartford Civic Ctr. 16,294
2/13/1990 L 90 94 at Providence 3 Providence, RI Providence Civic Ctr. 13,106
1/12/1984 L 63 65 2OT Villanova 4 Landover, MD Capital Centre 9,032
3/22/1987 L 73 88 vs Providence 4 Louisville, KY Freedom Hall 16,944
11/27/1981 L 61 70 vs SW Louisiana St. 5 Anchorage, AK Buckner Fieldhouse 3,600
11/29/1981 L 46 47 vs Ohio St. 5 Anchorage, AK Buckner Fieldhouse 1,500
12/15/1982 L 61 62 American 5 Landover, MD Capital Centre 9,902
12/27/1985 L 64 78 at Texas-El Paso 5 El Paso, TX Special Events Ctr. 12,222
2/21/1990 L 62 63 St. John's 5 Landover, MD Capital Centre 13,748
12/15/1990 L 60 71 Texas-El Paso 5 Landover, MD Capital Centre 8,037
1/10/1996 L 56 75 at Pittsburgh 5 Pittsburgh, PA Civic Arena 12,080
3/6/2013 L 57 67 at Villanova 5 Philadelphia, PA Wells Fargo Center 13,685
1/27/1996 L 72 83 at St. John's 6 New York, NY Madison Sq. Garden 13,888
2/9/2008 L 51 59 at Louisville 6 Louisville, KY Freedom Hall 20,083
2/3/2010 L 64 72 South Florida 7 Washington, DC Verizon Center 12,207
2/14/2010 L 68 71 at Rutgers 7 New Brunswick, NJ Rutgers Ath. Ctr. 6,225
1/17/1982 L 70 75 at Syracuse 8 Syracuse, NY Carrier Dome 25,623
1/3/1987 L 63 74 Seton Hall 8 Landover, MD Capital Centre 6,472
2/27/1996 L 77 84 at Providence 8 Providence, RI Providence Civic Ctr. 13,106
11/19/2006 L 62 75 Old Dominion 8 Washington, DC McDonough Gym 2,500
2/16/2008 L 70 77 at Syracuse 8 Syracuse, NY Carrier Dome 31,327
3/23/2008 L 70 74 vs Davidson 8 Raleigh, NC RBC Center 19,477
3/21/2013 L 68 78 vs Fla. Gulf Coast 8 Philadelphia, PA Wells Fargo Center 20,328